General

• Beta-lactamase (ß-lactamases) are enzymes produced by bacteria that provide multi-resistance to ß-lactam antibiotics such as penicillin, cephamycins.
  Beta-lactamase provides antibiotic resistance by breaking the antibiotics structure.
  These antibiotics all have a common element in their molecular structure: a four-atom ring known as a ß-lactam.
  Through hydrolysis, the lactamase enzyme breaks the ß-lactam ring open, deactivating the molecule's antibacterial properties.

History

• A diposable slide containing a reagent cassette impregnated with nitrocefin for the rapid qualitative detection of beta-lactamase producing bacteria. Test in 60 minutes or less.

Related

References

• WikipediA
  https://en.wikipedia.org/wiki/Beta-lactamase