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Campylobacter jejuni

  • General information


    • Taxonomy
      Family: Campylobacteriaceae
      Arcobacter
      Campylobacter


      Natural habitats
      In the intestinal tract of animals.
      Man is infected by direct contact with infected animals or by consumption of contaminated water or food, especially chicken and sometimes raw milk

      Clinical significance
      C. jejuni and C. coli continue to be the most common Campylobacter species associated with diarrheal illness and produce clinically indistinguishable infections.

      In patients with gastroenteritis caused by C. jejuni / C. coli, patients symptoms range from none to severe, including fever, abdominal cramping, and diarrhea (with or without blood/fecal white cells), that lasts several days to more than one week.

      Symptomatic infections
      are usually self-limited, but relapses may occur in 5 to 10% of untreated patients.

      Campylobacter infections may mimic acute appendicitis and result in unnecessary surgery.

      C. jejuni is the most often recognized infection preceding the development of Guillain-Barré syndrome.

      C. jejuni is in humans the most isolated.

      The most common condition is enteritis, a large number of patients followed by acute colitis (enterocolitis).

      Campylobacter infections may occur as acute appendicitis, which is sometimes unnecessary surgery.

      Guillain-Barré syndrome,
      and reactive arthritis may be the result of a Campylobacter infection.

  • Gram stain

    • Gram negative curved, S-shaped, or spiral rods,

      0.2-0.9 x 0.5-5 µm

      Rods may form spherical or coccoid bodies in old cultures or cultures exposed to air for prolonged periods.

  • Culture characteristics

    • Microaerophilic

      BA: colonies may be low, flat, grayish, finely granular, and translucent appearance with an irregular edge, and a tendency to swarm and merge or may be round, 1-2 mm diameter, raised, convex, smooth, shiny, with an entire, translucent edge and a darker, opaque center.

      Usually weakly α-hemolytic.

      Butzler agar = Campylobacter Selective Agar
      After 24-48 hours flat, moist and shiny colonies.
      In the thick areas inoculated colonies get a metallic gray blue tint.
      They are able to swarm on the culture medium in part or sometimes in whole.
      Sometimes round colonies with smooth edges, shiny and with a diameter of 2-3 mm.

      CCDA agar = Campylobacter Blood-Free Selective Medium
      Same as Butzler

      anaeroob/35-37ºC

  • Characteristics

  • References

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