Aggregatibacter aphrophilus

  • General information

    • the following information is not yet verified
      Family: Pasteurellaceae, previously: Haemophilus
      (formerly Haemophilus paraphrophilus).

      Natural habitats
      Occur in the mouth and oropharynx of healthy individuals.

      It is a frequent member of the microflora of human dental plaque, particularly between the teeth and in the gingival pockets

      Clinical significance
      Has been isolated from blood, spinal fluid, peritoneum, pleura, wounds and jaw infections.

      Opportunistic pathogen occasionally implicated in subacute endocarditis, brain abscesses, sinusitis, arthritis and osteomyelitis often caused by dental treatments that cause a break of the oral mucosal barrier and a temporary bactereamia.

  • Gram stain

    • the following information is not yet verified
      Gram negative short rods,

      0.4-0.6 x 1.5-1.7 µm,

      occasional filamentous forms.

  • Culture characteristics

    • the following information is not yet verified

      Facultative anaerobic

      5% CO2 improves the growth

      Colonies are high convex, granular, yellowish, opaque, 1.0-1.5 mm within 24 hours.


      Some isolates are V-factor dependent

      When grown in broth bacteria form granules at the bottom and up the sides of the tube (“tiny colonies”), while subsequent cultures become less adherent and exhibit uniform turbidity.

      McConkey no growth

      BBAØ growth

  • Characteristics

  • References

    • James Versalovic et al.(2011) Manual of Clinical Microbiology 10th Edition

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