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pseudomembranous colitis


Klinikum Dritter Orden, MünchenAbteilung Innere Medizin

https://commons.wikimedia.org/wiki/File:Pseudomembranoese_Colitis_Endo3.jpg

Clostridium difficile

  • General information

    • the following information is not yet verified
      Taxonomy
      Family: Clostridiaceae

      Natural habitats
      They inhabits the microflora of intestines of humans. Around 3% of healthy adults and up to 70% of babies have a number of C. difficile bacteria living in their gut.

      However, the number of C. difficile bacteria is kept very low and in control by the millions of harmless bacteria in the intestines that aid in digestion.

      Clinical significance
      Is the major cause of antibiotic associated pseudomembranous colitis, is it also the most frequently identified cause of hospital acquired diarrhea.

  • Gram stain

    • the following information is not yet verified
      Gram positive rods,

      0.5-0.9 x 3.0-16.9 µm.

      Spores oval / subterminal or terminal
      Swelling of the cell negative

  • Culture characteristics

    • the following information is not yet verified

      Obligate anaerobic

      BBAØ
      Colonies are 2-5 mm, circular, occasionally rhizoid, flat or low convex, opaque, grayish or whitish, and have a matt to glossy surface.

      Nonhemolytic.

      Fluorescence pale green

      Odor horse stable

  • Characteristics

  • References


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