Methylobacterium rhodinum

  • General information

    • the following information is not yet verified
      Family: Methylobacteriaceae

      Natural habitat
      They are isolated mostly from vegetation, but may also occasionally be found in the hospital enviroment.
      Tap water has been implicated as a possible agent of transmission in hospital environment.

      Methylobacterium species are a cause of health care-associated infections, including infections in immunocompromised hosts.
      The ability of Methylobacterium to form biofilms and to develop resistance to high temperatures, drying, and desinfecting agents may explain the colonization of Methylobacterium in the hospital environment in e.g. endoscopes.
      Due to its slow growth, it can be easily missed during microbiological surveillance of endoscope reprocessing.

      They are able to utilize methanol as a sole source of carbon and energy, although this characteristic may be lost on subculture.

      Clinical significance
      They have been reported to cause septicemia, continous ambulatory peritoneal dialysis related peritonitis, skin ulcers, synovitis, and other infections often in immunocompromised patients, as well as pseudoinfections.

  • Gram stain

    • the following information is not yet verified
      Gram-negative bacilli
      Cells are pleomorphic, vacuolated rods that stain poorly and may resist decoloration
      They have cell inlusions (sudanophilic)

  • Culture characteristics

    • the following information is not yet verified

      Obligate aerobic
      Optimum growth occurs between 25 and 30°C.

      Growth is fastidious on ordinary media (like blood agar), producing 1 mm diameter colonies after 4-5 days.
      They are very small, dry and coral pink.

      Sabouraud / LEG-, R2A agar
      Red colonies

      no growth

      Colonies appear dark due to absorption of UV-light.

  • Characteristics

  • References

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