Aggregatibacter actinomycetemcomitans
A) "rough" colony morphology of a clinical isolateB) "smooth" colony morphology of a spontaneous variant
Dr David Figurski
http://www.intechopen.com/books/genetic-manipulation-of-dna-and-protein-examples-from-current-research/targeted-mutagenesis-in-the-study-of-the-tight-adherence-tad-locus-of-aggregatibacter-actinomycetemc
Bone loss from aggressive periodontitis that led to an exposed furcation on an upper molar.
From wikipedia, the free encyclopedia
the following information is not yet verified
Taxonomy
Family: Pasteurellaceae
Genus: Aggregatibacter actinomycetemcomitans
Formerly: Actinobacillus
Natural habitat
Part of the normal flora of the mouth and pharynx
Clinical significance
It is one of the bacteria that might be implicated indestructive periodontal disease.
It is an oral commensal often found in association with localized aggressive periodontitis, a severe infection of the periodontium.
It is also associated with non-oral infections, such as abscesses (abdominal, brain, facial, hand, mediastinal and thyroid) and from cases of actinomycosis, endocarditis, meningitis, pneumonia, septicemia and vertebral osteomyelitis.
the following information is not yet verified
Gram negative coccobacillary rods,
0.3-0.5 x 0.6-1.4 µm,
They may occur singly, in pairs or in small (big) clumps and show the tendency to bipolar staining.
This gives an appearance of a "Morse code" of dots and dashes.
Cells have a microcapsule.
Facultative anaerobic
5% CO2 improves the growth
BA: colonies are small, 0.5-3 mm, no hemolysis, they adhere to the agar and are described as starlike or “crossed cigars”.
Colonies may sometimes have a rough surface and they become mucoid and non-adherent after repeated subculture.
Broth: when grown in broth bacteria form granules at the bottom and up the sides of the tube (“tiny colonies”), while subsequent cultures become less adherent and exhibit uniform turbidity.
McConkey: no growth
BBAØ: growth
James Versalovic et al.(2011) Manual of Clinical Microbiology 10th Edition
Karen C. Carrol et al (2019) Manual of Clinical Microbiology, 12th Edition